Inmaculada (Ada) Silos-Santiago is an MD, PhD from University of Cantabria, Spain. She was Research Associate Professor at the Dept. of Neurology and Neurological Surgery, Medical School, Washington University; Visiting Professor, Dept. of Medicine Harvard University, Medical School and Adjunct Associate Professor, Department of Molecular and Experimental Medicine, The Scripps Research Institute. Ada led gene discovery and preclinical pharmacology teams at Millennium, Vertex and Ironwood Pharmaceuticals as well as at Decibel Therapeutics. Working cross-functionally with Discovery and Development organizations she has delivered multiple drug candidates to clinical development in different disease indications and obtained FDA approval for Linzess, an oral peptide, for the treatment of IBS. Ada and her team identified the MOA of Linzess as a visceral analgesic unveiling a new endogenous pathway involved in the modulation of visceral pain. After Decibel Therapeutics, Ada started her consulting firm where she works with companies helping their Drug Discovery and Clinical Development teams. During her career, both in academia and industry, Ada has co-authored more than 100 scientific publications and more than 70 patents. Ada is an avid hiker and loves to cook for family and friends.
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